Small Airway Obstruction in COPD

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منابع مشابه

The Relationship between the Severity of Airway Obstruction and COPD Diagnostic Questionnaire Score in COPD Patients

Background & objectives: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow limitation and systemic inflammation which is also associated with pulmonary and extra-pulmonary complications. COPD Diagnostic Questionnaire (CDQ) is a valid questionnaire that is used to identify patients with COPD. The purpose of this study was to determine the relationship between ...

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CHRONIC OBSTRUCTIVE PULMONARY DISEASE Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD

R A O’Donnell, C Peebles, J A Ward, A Daraker, G Angco, P Broberg, S Pierrou, J Lund, S T Holgate, D E Davies, D J Delany, S J Wilson, R Djukanovic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....

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Relationship between peripheral airway dysfunction, airway obstruction, and neutrophilic inflammation in COPD.

BACKGROUND Considerable research has been conducted into the nature of airway inflammation in chronic obstructive pulmonary disease (COPD) but the relationship between proximal airways inflammation and both dynamic collapse of the peripheral airways and HRCT determined emphysema severity remains unknown. A number of research tools have been combined to study smokers with a range of COPD severit...

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Small airway obstruction in patients with rheumatoid arthritis

This work was intended to evaluate the prevalence of obstructive small-airway disease in patients with rheumatoid arthritis (RA) and its association with clinical characteristics. Pulmonary function testing (PFT) and high-resolution computed tomography (HRCT) were performed on 189 consecutive RA patients. Each case was diagnosed based on abnormal HRCT findings. We defined obstructive dysfunctio...

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Airway Inflammation in COPD*

Inflammation of the airways has been regarded as a cardinal pathophysiologic feature of asthma for some 20 years. This concept has been based on evidence from a variety of sources: the histologic changes in the airway wall, hyperresponsiveness of the asthmatic airways to a wide range of natural and pharmacologic agents, the presence of activated inflammatory and immune cells and their mediators...

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ژورنال

عنوان ژورنال: Chest

سال: 2013

ISSN: 0012-3692

DOI: 10.1378/chest.12-1766